- Evaluation of changes in random blood glucose and body mass index during and after completion of chemotherapy in children with acute lymphoblastic leukemia
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Kyong-Won Bang, Soo Young Seo, Jae Wook Lee, Pil-Sang Jang, Min Ho Jung, Nack-Gyun Chung, Bin Cho, Dae-Chul Jeong, Byung Kyu Suh, Hack-Ki Kim
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Clin Exp Pediatr. 2012;55(4):121-127. Published online April 30, 2012
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Purpose Improved survival of patients with childhood acute lymphoblastic leukemia (ALL) has drawn attention to the potential for late consequences of previous treatments among survivors, including metabolic syndrome. In this study, we evaluated changes in 3 parameters, namely, random blood glucose, body mass index (BMI), and Z score for BMI (Z-BMI), in children with ALL during chemotherapy and after completion of... |
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- Outcome of allogeneic hematopoietic stem cell transplantation for childhood acute lymphoblastic leukemia in second complete remission: a single institution study
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Eun-Jung Lee, Ji Yoon Han, Jae Wook Lee, Pil-Sang Jang, Nack-Gyun Chung, Dae-Chul Jeong, Bin Cho, Hack-Ki Kim
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Clin Exp Pediatr. 2012;55(3):100-106. Published online March 16, 2012
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Purpose The survival rate for childhood acute lymphoblastic leukemia (ALL) has improved significantly. However, overall prognosis for the 20 to 25% of patients who relapse is poor, and allogeneic hematopoietic stem cell transplantation (HSCT) offers the best chance for cure. In this study, we identified significant prognostic variables by analyzing the outcomes of allogeneic HSCT in ALL patients in second complete... |
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- Effect of p16 on glucocorticoid response in a B-cell lymphoblast cell line
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Sun-Young Kim, Kyung-Yil Lee, Dae-Chul Jeong, Hak-Ki Kim
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Clin Exp Pediatr. 2010;53(7):753-758. Published online July 31, 2010
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Purpose It has been suggested that p16 has a role in glucocorticoid (GC)-related apoptosis in leukemic cells, but the exact mechanisms have yet to be clarified. We evaluated the relationship between the GC response and p16 expression in a lymphoma cell line. MethodsWe used p16 siRNA transfection to construct p16-inactivated cells by using the B-cell lymphoblast cell line NC-37. We compared glucocorticoid... |
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- CMV antigenemia following pediatric hematopoietic stem cell transplantation : risk factors and outcomes
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Eun-Young Cho, Young-Shil Park, Dae-Hyung Lee, Ji Kyoung Park, Sangrhim Choi, Sun Young Kim, Pil-Sang Jang, Dong-Gun Lee, Nak-Gyun Chung, Jong Hyun Kim, Dae-Chul Jeong, Bin Cho, Jae Gyun Hur, Jin Han Kang, Hack-Ki Kim
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Clin Exp Pediatr. 2006;49(2):173-180. Published online February 15, 2006
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Purpose : Cytomegalovirus(CMV) infection still remains as a major cause of morbidity and mortality after stem cell transplantation. In this study, we analyzed the results of antigenemia-guided pre- emptive therapy among children with allogeneic hematopoietic stem cell transplantation to determine the incidence and risk factors associated with CMV antigenemia, and evaluated the efficacy of the CMV antigenemia based preemptive therapy.... |
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- Short-term follow up of thyroid function after pediatric hematopoietic stem cell transplantation
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Seon-Ju Lee, Jae-Wook Lee, Dae-Hyoung Lee, Young-Joo Kwon, Young-Shil Park, Hui Sung Hwang, Sun Young Kim, Ji Kyoung Park, Pil-Sang Jang, Min-Ho Jung, Nak-Gyun Chung, Dae-Chul Jeong, Bin Cho, Hack-Ki Kim, Byung-Churl Lee
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Clin Exp Pediatr. 2006;49(11):1211-1215. Published online November 15, 2006
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Purpose : In this study, we analyzed the short term changes of thyroid function, incidence and risk factors of thyroid dysfunction soon after allogeneic hematopoietic stem cell transplantation (HSCT) in children.
Methods : We enrolled 80 pediatric patients following allogeneic HSCT, at the Catholic HSCT center between January, 2004 and February, 2006. Serum TSH (thyroid stimulating hormone), total serum thyroxine and... |
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